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Synthesis and cytotoxic activity of indolyl thiazoles
C J Moody1, J R Roffey, M A Stephens
1Department of Chemistry, Loughborough University, Leicestershire, UK.
Anti-Cancer Drugs
|June 1, 1997
Abstract:
A number of indolyl thiazoles have been prepared and evaluated for their antitumor properties. The compounds were synthesized from the appropriate indole, building up the thiazole ring using the Hantzsch reaction. Cytotoxic activity was measured in the human breast cancer cell line SKBr3 using the MTT assay.