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Related Experiment Videos

Diaphragm thickening during inspiration

D Cohn1, J O Benditt, S Eveloff

  • 1Department of Medicine, Memorial Hospital of Rhode Island, Pawtucket, 02860, USA.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|July 1, 1997
PubMed
Summary

Two-dimensional ultrasound accurately measures diaphragm thickness (Tdi). Diaphragm thickening increases with lung volume, correlating with vital capacity changes during inspiration.

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Area of Science:

  • Medical Imaging
  • Pulmonary Physiology
  • Anatomy

Background:

  • One-dimensional ultrasound measurements of diaphragm thickness (Tdi) during inspiration exceeded predictions from other radiographic methods.
  • Two-dimensional (2-D) ultrasound offers superior anatomic definition for diaphragm assessment.

Purpose of the Study:

  • To reevaluate the relationship between lung volume and Tdi using 2-D ultrasound.
  • To establish the accuracy and reproducibility of 2-D ultrasound for measuring Tdi.

Main Methods:

  • 2-D ultrasound with a 7.5-MHz transducer was used to measure Tdi in 26 cadavers for accuracy and reproducibility.
  • Diaphragm images were obtained in nine subjects at five lung volumes (residual volume to total lung capacity) to study Tdi-lung volume relationship.

Main Results:

  • 2-D ultrasound measurements of Tdi correlated significantly with ruler measurements in cadavers (R2 = 0.89).
  • Diaphragm thickness increased with lung volume in subjects, with a steeper increase at higher lung volumes (R2 = 0.99).
  • Mean Tdi increase from residual volume to total lung capacity was 54%.

Conclusions:

  • 2-D ultrasound is an accurate method for measuring Tdi.
  • Diaphragm thickening during inspiration from residual volume to total lung capacity averages 54%, aligning with predictions from diaphragm shortening.

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