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[Relapsing polychondritis with mental disorders: a case report]

T Watanabe1, Y Yasuda, H Tanaka

  • 1Department of Neurology, Otsu Red Cross Hospital.

Rinsho Shinkeigaku = Clinical Neurology
|March 1, 1997
PubMed
Summary

Relapsing polychondritis can cause mental disorders, including confusion and cognitive decline. Early corticosteroid treatment may improve these neurological symptoms, as seen in this Japanese case.

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Area of Science:

  • Neurology
  • Rheumatology
  • Psychiatry

Background:

  • Relapsing polychondritis (RP) is a rare autoimmune disease affecting cartilage.
  • Neurological manifestations of RP are uncommon but can be severe.

Observation:

  • A 60-year-old Japanese man with RP experienced disorientation, euphoria, and cognitive decline.
  • Clinical presentation included auricular and nasal chondritis, and sensorineural hearing loss.

Findings:

  • EEG revealed diffuse slow wave abnormalities.
  • Cerebrospinal fluid (CSF) analysis showed pleocytosis and elevated protein.
  • MRI demonstrated medial temporal lobe enhancement and edema.

Implications:

  • This case highlights RP's potential to present with psychiatric and cognitive symptoms.

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  • Prompt corticosteroid therapy led to significant improvement in neurological findings.
  • This is the first reported Japanese case of RP with mental disorders.