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Cellular immune recognition and the biological role of major transplantation antigens

R M Zinkernagel1

  • 1Institute of Experimental Immunology, University of Zurich, Switzerland.

Bioscience Reports
|April 1, 1997
PubMed

The experiments leading to the discovery of MHC-restricted T-cell killing of virus-infected cells are described. The implications of MHC- and HLA-restricted T-cell killing for the development of new vaccines and for the understanding of autoimmune disease are discussed.

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