Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ureteroscopic biopsy: technique and specimen preparation

E Tawfiek1, M Bibbo, D H Bagley

  • 1Department of Urology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.

Urology
|July 1, 1997
PubMed
Summary

Precise ureteroscopic biopsy techniques are vital for diagnosing upper tract neoplasms. Detailed sample handling and processing improve diagnostic accuracy for urothelial cancers.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A PC-based system for the objective analysis of histologic specimens through quantitative contextual karyometry.

Applied optics·2010
Same author

Fluoroscopic placement of double-pigtail ureteral stents.

Diagnostic and therapeutic endoscopy·2008
Same author

Study of viral integration of HPV-16 in young patients with LSIL.

Journal of clinical pathology·2003
Same author

Processing liquid-based gynecologic specimens: comparison of the available techniques.

Acta cytologica·2001
Same author

Long-term effects of ureteroscopic laser lithotripsy on glomerular filtration rate in the face of mild to moderate renal insufficiency.

Journal of endourology·2001
Same author

The problematic lower pole stone.

The Journal of urology·2001

Area of Science:

  • Urology
  • Cytopathology
  • Oncology

Background:

  • Ureteroscopic biopsies yield small tissue samples, necessitating optimized techniques.
  • Accurate diagnosis and grading of upper tract neoplasms depend on meticulous sample handling.

Purpose of the Study:

  • To detail a reproducible ureteroscopic biopsy technique for upper tract neoplasms.
  • To enhance diagnostic accuracy through standardized specimen retrieval and processing.

Main Methods:

  • Patients underwent retrograde ureteropyelography and ureteroscopy for diagnosis.
  • Small-diameter rigid and flexible ureteroscopes were used to examine the collecting system.
  • Samples were retrieved via aspiration, saline lavage, or direct biopsy using forceps; multiple samples were obtained.

Main Results:

  • Fresh specimens were promptly delivered to cytopathology for cytospin evaluation.
  • Cell blocks were prepared for any visible tissue, aiding histological assessment.
  • Standardized specimen handling significantly improved diagnostic and grading capabilities.

Conclusions:

  • The described ureteroscopic biopsy technique is reproducible and enhances diagnostic accuracy.
  • Meticulous sample handling and processing are critical for diagnosing upper tract neoplasms ureteroscopically.

Related Experiment Videos