Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Roles for motility in bacterial-host interactions

K M Ottemann1, J F Miller

  • 1Department of Molecular and Cell Biology, University of California, Berkeley 94720, USA.

Molecular Microbiology
|June 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

MICROBIOME. A unified initiative to harness Earth's microbiomes.

Science (New York, N.Y.)·2015
Same author

T-cell antigen receptors: fact and artefact.

Immunology today·2014
Same author

Amelogenesis imperfecta; report of a case.

United States naval medical bulletin·2010
Same author

Intestinal helminthiasis; clinical survey of 618 cases of infection with common intestinal helminths in children.

The American journal of tropical medicine and hygiene·2010
Same author

Displacement of the mediastinum due to pulsion by a caseous tuberculous lung without pleural effusion; report of a case in an infant.

The Journal of pediatrics·2010
Same author

Parabolic shape of a tapered fused coupler: comparison with experiment.

Applied optics·2010

Bacterial motility offers advantages like nutrient acquisition but incurs costs such as metabolic burden. Strict regulation of this movement is crucial for bacterial survival and infection cycles.

Area of Science:

  • Microbiology
  • Bacterial Pathogenesis
  • Cellular Biology

Background:

  • Directed movement (motility) provides significant advantages for prokaryotes adapted to hosts.
  • Benefits include enhanced nutrient uptake, evasion of toxins, host seeking, and colonization site selection.
  • Motility also presents substantial costs, including metabolic and energetic burdens, and immune system recognition.

Purpose of the Study:

  • To explore the advantages and disadvantages of bacterial motility.
  • To understand the regulation of motility apparatus synthesis in prokaryotes.
  • To examine the role of motility in various stages of bacterial-host interactions.

Main Methods:

  • Review of existing literature on bacterial motility.
  • Analysis of studies on bacterial-host interactions.

Related Experiment Videos

  • Examination of regulatory mechanisms controlling flagellar synthesis.

    • Main Results:

    • Motility aids in nutrient acquisition, toxin avoidance, host colonization, and transmission.
    • Costs of motility involve significant metabolic and energetic expenditures.
    • Synthesis of the motility apparatus is tightly regulated in response to environmental cues.
    • Motility plays a critical role throughout the infectious cycle in bacterial-host interactions.

    Conclusions:

    • Bacterial motility is a double-edged sword, offering survival benefits at a considerable cost.
    • The strict control over motility synthesis highlights its importance in bacterial adaptation and pathogenesis.
    • Understanding motility regulation is key to deciphering bacterial-host dynamics.