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Related Experiment Videos

Psoriasis and stress

R H Seville

    The British Journal of Dermatology
    |September 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Stress preceding psoriasis onset may indicate a better prognosis. This study followed 132 patients, finding a link between recalled stress and improved outcomes for psoriasis patients.

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    Area of Science:

    • Dermatology
    • Psychoneuroimmunology
    • Epidemiology

    Background:

    • Psoriasis is a chronic inflammatory skin condition.
    • The role of psychological stress in psoriasis onset and progression is under investigation.
    • Dithranol is a topical treatment used for psoriasis.

    Purpose of the Study:

    • To investigate the relationship between recalled psychological stress and psoriasis prognosis.
    • To determine the incubation period between stress incidents and psoriasis development.
    • To assess the predictive value of stress recall on treatment outcomes.

    Main Methods:

    • A cohort of 132 psoriasis patients, cleared with dithranol, were followed for 3 years.
    • Patients recalled specific stress incidents preceding psoriasis onset.

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  • A control group was used to exclude chance associations between stress and psoriasis.

    • Main Results:

    • The incubation time from stress to psoriasis onset ranged from 2 days to 1 month.
    • 51% of patients recalled specific stress within a month before their first attack.
    • Psoriasis patients recalling stress had a significantly better prognosis compared to those who did not.

    Conclusions:

    • Recalled psychological stress preceding psoriasis onset is associated with a better prognosis.
    • Stress may serve as a potential biomarker for treatment response in psoriasis.
    • Further research is warranted to elucidate the mechanisms underlying this association.