Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Post-kala-azar dermal leishmaniasis

H S Girgla, R A Marsden, G M Singh

    The British Journal of Dermatology
    |September 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Biochemical, gas exchange, and chlorophyll fluorescence analysis of maize genotypes under drought stress reveals important insights into their interaction and homeostasis.

    Photosynthetica·2024
    Same author

    Urticaria Pigmentosa and Diarrhoea (A case report).

    Indian journal of dermatology and venereology·2017
    Same author

    Reiter's Disease - Clinical Profile of Epidemic Form.

    Indian journal of dermatology, venereology and leprology·2017
    Same author

    Comparative Evaluation of Ampicillin and Trimethoprim Sulfamoxole Combination in Gonorrhoea.

    Indian journal of dermatology, venereology and leprology·2017
    Same author

    Digital Patterns in Vitiligo.

    Indian journal of dermatology, venereology and leprology·2017
    Same author

    Erythrodermic pustular psoriasis triggered by intravesical bacillus Calmette-Guérin immunotherapy.

    Clinical and experimental dermatology·2012
    Same journal

    Biett's Sign: A Diagnostic Clue to Secondary Syphilis.

    The British journal of dermatology·2026
    Same journal

    Shallow Cuts, Deeper Issues: The Primacy of Deep Margins in Cutaneous Squamous Cell Carcinoma.

    The British journal of dermatology·2026
    Same journal

    Management Patterns and Repigmentation Outcomes in Pediatric Segmental Versus Non-segmental Vitiligo: A Single-center Retrospective Study (2015-2024).

    The British journal of dermatology·2026
    Same journal

    Quality-of-Life Measurement in Migrants and Other Vulnerable Groups: Experience with Skindex-16 in Malta and Lebanon.

    The British journal of dermatology·2026
    Same journal

    Does loss of chromosome Y in blood contribute to the sex disparity of dermatitis and eczema at older ages?

    The British journal of dermatology·2026
    Same journal

    Soluble CD83 reverses alopecia areata via IDO-mediated Treg cell activation.

    The British journal of dermatology·2026
    See all related articles

    This study on post-kala-azar dermal leishmaniasis found that lesion type and parasitic load influenced treatment response to stibophen. Nodular lesions with high Leishmania parasite counts showed limited improvement.

    Area of Science:

    • Dermatology
    • Infectious Diseases
    • Parasitology

    Background:

    • Post-kala-azar dermal leishmaniasis (PKDL) is a complication of visceral leishmaniasis.
    • PKDL presents with diverse cutaneous manifestations, posing diagnostic challenges.
    • Understanding treatment responses is crucial for managing PKDL.

    Purpose of the Study:

    • To describe clinical presentations of PKDL in ten patients.
    • To evaluate the efficacy of stibophen treatment in relation to lesion type and parasitic load.
    • To discuss differential diagnosis challenges, particularly with leprosy.

    Main Methods:

    • Case series of ten PKDL patients (2 female, 8 male; aged 17-47).
    • Clinical assessment of macular and nodular lesions.

    Related Experiment Videos

  • Microscopic identification of Leishman-Donovan bodies.
  • Monitoring response to stibophen treatment.

    • Main Results:

    • Two patients with macular lesions and low parasite load responded well to stibophen.
    • Five patients with mixed macular and nodular lesions showed partial nodule regression.
    • Three patients with nodular lesions and high parasite load had only temporary improvement with stibophen.

    Conclusions:

    • Treatment response to stibophen in PKDL appears correlated with lesion type and parasitic burden.
    • Nodular lesions with high Leishmania parasite load are less responsive to stibophen.
    • Distinguishing PKDL from leprosy requires careful clinical and parasitological evaluation.