Related Experiment Video
Updated: Aug 7, 2026

A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome
Published on: October 2, 2018
Polycystic ovary syndrome. An autoimmune disease?
1Department of Obstetrics and Gynecology, Hadassah Hebrew University Medical Center Ein-Kerein, Jerusalem, Israel.
Objective:
To determine whether there is an autoimmune cause of polycystic ovary disease (PCOD) implicating antiovarian antibodies in the pathophysiology of the syndrome.
Study Design:
This study examined 31 women diagnosed as having PCOD according to internationally recognized criteria and who attended our infertility clinic during 1994-1995.
Results:
We could not confirm the findings of previous studies. Only one patient in our group with type II diabetes mellitus had antiovarian antibodies present in her serum.
Conclusion:
It seems that an autoimmune mechanism probably is not of prime importance in this multifaceted syndrome.
Related Concept Videos
Oogenesis
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune system...
Oogenesis
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is known...
Cushing Syndrome II: Pathophysiology
Type I Diabetes I: Introduction
Type I Diabetes II: Pathophysiology

