A proton magnetic resonance investigation on 1:1 cytidine and guanosine silver(I) complexes

Solid 1:1 silver (I) complexes with cytidine and guanosine have been isolated from aqueous solutions at pH 10. PMR spectra in deuterodimethylsulfoxide-d6 solutions have been measured. Results show that binding sites for cytidine are the nitrogen atom of the NH2 group and N-3. In the Agguanosine complex, pmr data are in agreement with the formation of a chelate ring involving N-7 and O-6. Chemical shift changes of the amino protons show that NH2 is also another binding site.