[The immunological aspects in the HIV/AIDS-tuberculosis association in children]

HIV-infected subjects are submitted to various immunity disorders, the function of immune competent cells disturbing, the most important one, resulting in severe opportunistic infections. The progressive depletion of CD4 subset of lymphocytes in HIV-infected persons is the most significant one. When HIV infection is associated to tuberculosis there is a more accelerated immune deterioration. The immunological investigation consisted in the determination of cell-mediated immune mechanisms (PPD skin testing, lymphocyte count, subsets of lymphocytes) as well as those humorally mediated (Ig classes, anti-mycobacteria antibodies).