[Immune and fibrinolytic system functions in the cardiac manifestations of atherosclerosis]

A total of 77 patients with various clinical forms of cardiac atherosclerosis were examined. Fibrinolytic and immune systems were studied together with blood plasma concentration of fibronectine. Disorders of the same type have been revealed of immunologic reactivity manifested by enhancement of humoral immunity and impairment of cellular immunity, increase in coagulative activity, decline in the activity of the system of fibrinolysis. Latent DBS syndrome recorded in the above patients associated with decline in the activity of monocytic-macrophagal link of immunity and low fibrinolytic potential is a pathogenetic prerequisite of progression of atherosclerosis indicating main trends in drug therapy.