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Secondary osteoporosis

D M Reid1, J Harvie

  • 1Department of Medicine and Therapeutics, University of Aberdeen, Foresterhill, UK.

Bailliere'S Clinical Endocrinology and Metabolism
|April 1, 1997
PubMed
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Secondary osteoporosis, linked to specific risk factors or low bone mass, affects many fractures, especially in men. This review focuses on key causes, including avoidable ones and corticosteroid-induced osteoporosis, with prevention and treatment strategies.

Area of Science:

  • Endocrinology and Bone Metabolism
  • Pharmacology and Toxicology

Background:

  • Secondary osteoporosis is a significant contributor to osteoporotic fractures, particularly in men.
  • It is diagnosed in the presence of established disease-related risk factors for fracture or low bone mass.

Purpose of the Study:

  • To review important causes of secondary osteoporosis.
  • To emphasize corticosteroid-induced osteoporosis as a major iatrogenic cause.
  • To highlight avoidable causes and review prevention and treatment strategies.

Main Methods:

  • Literature review focusing on significant causes of secondary osteoporosis.
  • Specific emphasis on iatrogenic causes, particularly corticosteroid-induced osteoporosis.
  • Identification of potentially avoidable causes and review of management options.

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Main Results:

  • Secondary osteoporosis accounts for a substantial proportion of osteoporotic fractures.
  • Corticosteroid use is a primary iatrogenic cause of secondary osteoporosis.
  • Several avoidable factors contribute to secondary osteoporosis.

Conclusions:

  • Understanding and addressing the causes of secondary osteoporosis are crucial for fracture prevention.
  • Interventions targeting iatrogenic and avoidable causes can mitigate fracture risk.
  • Effective prevention and treatment strategies are available for secondary osteoporosis.