Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Renal osteodystrophy

K A Hruska1

  • 1Renal Division, Washington University, St Louis, MO, USA.

Bailliere'S Clinical Endocrinology and Metabolism
|April 1, 1997
PubMed
Summary
This summary is machine-generated.

Renal osteodystrophy, a complication of chronic kidney disease, has shifted from osteomalacia to adynamic bone disorder. This change is linked to treatments for secondary hyperparathyroidism and calcitriol deficiency, suggesting multifactorial causes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Physiological condition differentially affects the behavior and survival of two populations of sockeye salmon during their freshwater spawning migration.

Physiological and biochemical zoology : PBZ·2010
Same author

MicroRNA-223 is a key factor in osteoclast differentiation.

Journal of cellular biochemistry·2007
Same author

Function and effect of bone morphogenetic protein-7 in kidney bone and the bone-vascular links in chronic kidney disease.

European journal of clinical investigation·2006
Same author

New insights into mineral and skeletal regulation by active forms of vitamin D.

Kidney international·2006
Same author

Osteopontin.

Drug news & perspectives·2004
Same author

Differential growth factor control of bone formation through osteoprogenitor differentiation.

Bone·2004
Same journal

Phytoestrogen content in foods.

Bailliere's clinical endocrinology and metabolism·1999
Same journal

Soyfoods, isoflavones and risk of colonic cancer: a review of the in vitro and in vivo data.

Bailliere's clinical endocrinology and metabolism·1999
Same journal

Experimental studies on lignans and cancer.

Bailliere's clinical endocrinology and metabolism·1999
Same journal

Reproductive actions of phytoestrogens.

Bailliere's clinical endocrinology and metabolism·1999
Same journal

Phytoestrogens and inhibition of angiogenesis.

Bailliere's clinical endocrinology and metabolism·1999
Same journal

Phytoestrogens and diseases of the prostate gland.

Bailliere's clinical endocrinology and metabolism·1999
See all related articles

Area of Science:

  • Nephrology
  • Bone Metabolism
  • Mineral and Bone Disorders

Background:

  • Renal osteodystrophy is a common complication in chronic renal failure and end-stage renal disease.
  • The prevalence of aluminum-induced osteomalacia has decreased, leading to a shift in the primary bone pathology.
  • Adynamic bone disorder has become more prevalent than osteomalacia in patients with chronic kidney disease.

Purpose of the Study:

  • To discuss the changing nature of renal osteodystrophy.
  • To explore factors contributing to the pathogenesis of renal osteodystrophy beyond secondary hyperparathyroidism and calcitriol deficiency.
  • To review the presentation and treatment of renal osteodystrophy.

Main Methods:

  • Literature review on the evolution of renal osteodystrophy.

Related Experiment Videos

  • Analysis of factors contributing to adynamic bone disorder.
  • Discussion of current knowledge on pathogenesis, presentation, and treatment.

    • Main Results:

    • Adynamic bone disorder has largely replaced osteomalacia as the predominant form of renal osteodystrophy.
    • Suppression of osteitis fibrosa, calcitriol, and control of secondary hyperparathyroidism are implicated in the development of adynamic bone disorder.
    • Multiple factors, in addition to secondary hyperparathyroidism and calcitriol deficiency, contribute to renal osteodystrophy.

    Conclusions:

    • The pathogenesis of renal osteodystrophy is complex and multifactorial.
    • Understanding these factors is crucial for effective management and treatment strategies.
    • Further research is needed to fully elucidate the contributing factors and optimize patient care.