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Updated: Aug 12, 2026

Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions
06:50

Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions

Published on: January 26, 2024

Structural consensus in ligand-protein docking identifies recognition peptide motifs that bind streptavidin

N K Shah1, P A Rejto, G M Verkhivker

  • 1Agouron Pharmaceuticals, Inc., San Diego, California 92121, USA.

Proteins
|July 1, 1997
PubMed
Summary

Computational methods identified key features of streptavidin-peptide binding. The structural consensus criterion effectively predicts recognition motifs, revealing minimally frustrated energy landscapes for effective peptide binding.

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