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Primary hyperparathyroidism in two cats

E den Hertog1, M M Goossens, J S van der Linde-Sipman

  • 1Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrechi University, The Netherlands.

The Veterinary Quarterly
|June 1, 1997
PubMed
Summary
This summary is machine-generated.

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Primary hyperparathyroidism (PHP) in cats is rare but treatable. Surgical removal of parathyroid adenomas effectively resolved hypercalcaemia and associated symptoms in two feline patients.

Area of Science:

  • Veterinary Medicine
  • Endocrinology
  • Oncology

Background:

  • Primary hyperparathyroidism (PHP) is an uncommon endocrine disorder in domestic cats.
  • Clinical presentation often includes lethargy, anorexia, and vomiting due to hypercalcaemia.
  • Diagnostic challenges exist, especially when cervical masses are not palpable.

Observation:

  • Two neutered male domestic shorthair cats, aged 9 and 13 years, presented with hypercalcaemia and normo- to hypophosphataemia.
  • One cat had a palpable cervical mass with benign glandular cells on cytology; the other had elevated plasma parathyroid hormone (PTH) levels.
  • Both cats underwent surgical exploration and removal of a solitary parathyroid adenoma.

Findings:

  • Immunohistochemical analysis confirmed abundant PTH within the resected parathyroid adenomas.

Related Experiment Videos

  • Post-surgical normalization of plasma calcium and phosphate concentrations was observed in both cats.
  • Complete recovery without recurrence was noted during follow-up examinations.

    • Implications:

    • Surgical excision of parathyroid adenomas is an effective treatment for primary hyperparathyroidism in cats.
    • Early diagnosis and intervention can lead to uncomplicated recovery and long-term remission.
    • This case series highlights the importance of considering PHP in cats with unexplained hypercalcaemia.