Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Conventional haemofiltration during routine coronary bypass surgery

R M Babka1, J Petress, R Briggs

  • 1St Mary's Medical Center, Department of Surgical Services, Knoxville, TN 37917, USA.

Perfusion
|May 1, 1997
PubMed
Summary

Routine ultrafiltration during cardiopulmonary bypass (CPB) in coronary artery bypass surgery showed no significant benefits. This study found no improvements in blood loss, transfusion needs, or patient charges when using the COBE 1200 device.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From chaos to tranquillity: a modern approach to the identification, nomenclature and phylogeny of <i>Aspergillus</i>, <i>Penicillium</i> and other <i>Eurotiales</i>, including an updated accepted species list.

Studies in mycology·2026
Same author

Genetics by genetic algorithm: Defining an ideal platelet donor population to support patients with HLA-mediated alloimmune refractoriness.

Transfusion·2025
Same author

The structure of liquid carbon elucidated by in situ X-ray diffraction.

Nature·2025
Same author

Consequences of the Crisis in Social Care for Older Hospital Inpatients with Frailty.

Irish medical journal·2025
Same author

Inpatient referrals to a specialist falls and syncope service: prevalence of STOPPFall FRIDs and review of deprescribing patterns.

European journal of clinical pharmacology·2024
Same author

Phase transition kinetics of superionic H<sub>2</sub>O ice phases revealed by Megahertz X-ray free-electron laser-heating experiments.

Nature communications·2024

Area of Science:

  • Cardiovascular Surgery
  • Nephrology
  • Critical Care Medicine

Background:

  • Conventional ultrafiltration is recognized for reversing hemodilution during cardiopulmonary bypass (CPB).
  • Its routine application in coronary artery bypass surgery (CABG) warrants investigation for clinical and economic impacts.

Purpose of the Study:

  • To prospectively evaluate the efficacy of routine ultrafiltration during CPB in CABG patients.
  • To compare outcomes between patients receiving ultrafiltration and a control group.

Main Methods:

  • A prospective study involving 60 patients undergoing CABG, divided into two groups: 30 with ultrafiltration (Group A) and 30 without (Group B).
  • The COBE 1200 ultrafiltration device was utilized in Group A.
  • Key outcome measures included postoperative blood loss, blood transfusion requirements, weight gain, length of stay, and patient charges.

Related Experiment Videos

Main Results:

  • Group A (ultrafiltration) had a mean ultrafiltrate volume of 2510 ml.
  • Postoperative blood loss, bank blood transfused, postoperative weight gain, length of stay, and overall patient charges were comparable between Group A and Group B.
  • Specifically, mean 24-h blood loss was 440 ml (Group A) vs. 451 ml (Group B), and average patient charges were $33,706 (Group A) vs. $33,041 (Group B).

Conclusions:

  • Routine use of ultrafiltration during CPB in CABG surgery does not appear to improve the quality of patient care.
  • The technique did not demonstrate a reduction in postoperative blood loss, transfusion requirements, or hospital charges.
  • Further research may be needed to identify specific patient subgroups that could benefit from ultrafiltration during CPB.