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Bench to bedside: what have we learnt recently about headache?
1Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, UK. peterg@brain.ion.ucl.ac.uk
Current Opinion in Neurology
|June 1, 1997
Summary
Recent advances illuminate the complex mechanisms of head pain, detailing cranial pain transmission and the pathophysiology of migraine and cluster headache.
Area of Science:
- Neurology
- Pain Medicine
Background:
- Headache is a prevalent human ailment.
- Understanding the basic mechanisms of head pain has significantly advanced.
Purpose of the Study:
- To summarize recent progress in comprehending headache pathophysiology.
- To highlight advances in the anatomy and physiology of cranial pain transmission.
Main Methods:
- Review of recent scientific literature.
- Elucidation of pain pathways within the cranium.
Main Results:
- Significant progress in understanding the basic mechanisms of head pain.
- Advances in the pathophysiology of migraine.
- Progress in understanding cluster headache mechanisms.
Conclusions:
- The basic mechanisms of head pain are increasingly understood.
- Key advances have been made in the pathophysiology of primary headache disorders like migraine and cluster headache.