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Related Experiment Videos

Mechanical circulatory assistance: changing indications and options

W Piccione1

  • 1Department of Cardiovascular-Thoracic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL 60612, USA.

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
|June 1, 1997
PubMed
Summary

Left Ventricular Assist Devices (LVADs) show declining morbidity and mortality rates. Early LVAD implantation for heart failure patients awaiting transplantation improves outcomes and offers a viable alternative to heart transplants.

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Bridge to transplant with the HeartMate device.

Journal of cardiac surgery·2002
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Hypotension, acidosis, and vasodilatation syndrome post-heart transplant: prognostic variables and outcomes.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2001
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Improvement in quality of life outcomes 2 weeks after left ventricular assist device implantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2001
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A multicenter, randomized, controlled trial of Celsior for flush and hypothermic storage of cardiac allografts.

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Change in physical and psychosocial domains of quality of life from before to after discharge post left ventricular assist device implantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2001
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Left ventricular assist device implantation: short and long-term surgical complications.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2000

Area of Science:

  • Cardiovascular Medicine
  • Biomedical Engineering
  • Transplantation Surgery

Background:

  • Historically, Left Ventricular Assist Device (LVAD) implantation for long-term support was associated with high morbidity and mortality.
  • Advancements in device design, patient selection, and clinical expertise have led to improved outcomes.
  • Chronic heart failure patients awaiting transplantation face limited donor availability and the risk of end-organ dysfunction.

Purpose of the Study:

  • To evaluate the current status and future potential of LVADs in managing end-stage heart failure.
  • To highlight the benefits of early LVAD consideration for eligible patients.
  • To assess the implications of 'discharge to home' protocols for LVAD recipients.

Main Methods:

  • Review of clinical experience and design improvements in LVAD technology.

Related Experiment Videos

  • Evaluation of ongoing 'discharge to home' protocols for specific LVAD devices (Novacor and HeartMate).
  • Analysis of patient selection criteria for LVAD implantation.

    • Main Results:

    • Significant decline in morbidity and mortality rates associated with LVAD implantation.
    • Emerging data from 'discharge to home' protocols are expected to have major economic and quality-of-life impacts.
    • Current LVAD devices demonstrate a level of reliability supporting consideration as an alternative to heart transplantation.

    Conclusions:

    • Early LVAD implantation is recommended for chronic heart failure patients before irreversible end-organ damage occurs.
    • LVADs are becoming a reliable therapeutic option, offering hope for patients with limited transplant options.
    • LVADs provide a crucial alternative for patients not meeting traditional heart transplant criteria.