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Updated: Jul 27, 2026

Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model
Published on: August 5, 2021
[Surgical treatment of retinal detachment with multiple, giant and post-equatorial ruptures]
V V Ilńitskiĭ1, E O Saksonova, N V Guréva
1Department of Eye Diseases of State Medical University, Moscow.
Abstract:
A method for surgical treatment of grave detachment of the retina with multiple, giant, and postequatorial ruptures has been developed. The method consists in combined extrascleral filling making use of bichannel silicon explants. A total of 78 patients (78 eyes) were operated on. For control the results of 30 interventions on 30 eyes (30 patients) with similar injuries have been analyzed; in this group traditional methods of combined filling with standard silicon explants were used. The patients were followed up for up to 7 years. In the main group adherence of the retina was observed in 71.8% of cases in remote periods and in 82% after repeated surgery (relapses of retinal detachment occurred in 15.4% of cases). In controls complete adherence was attained in 60% of cases and in 76.7% of those operated on repeatedly (relapses occurred in 23.3%). The developed models of bichannel silicon explants are simpler and more effective than the traditional methods.

