Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Method for long-term intestinal access in the dog

M Wilsson-Rahmberg1, O Jonsson

  • 1Laboratory Animal Resources, Astra Hässle AB, Mölndal, Sweden.

Laboratory Animals
|July 1, 1997
PubMed
Summary

A novel nipple valve technique provides safe, long-term intestinal access in dogs. This method minimizes complications, avoids foreign materials, and maintains animal welfare, unlike traditional devices.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Measurement of the charge asymmetry in top quark pair production in <i>pp</i> collisions at [Formula: see text] using the ATLAS detector.

The European physical journal. C, Particles and fields·2015
Same author

Measurement of [Formula: see text] production with a veto on additional central jet activity in <i>pp</i> collisions at [Formula: see text] TeV using the ATLAS detector.

The European physical journal. C, Particles and fields·2015
Same author

Measurement of the top quark mass with the template method in the [Formula: see text] channel using ATLAS data.

The European physical journal. C, Particles and fields·2015
Same author

Search for heavy neutrinos and right-handed <i>W</i> bosons in events with two leptons and jets in <i>pp</i> collisions at [Formula: see text] with the ATLAS detector.

The European physical journal. C, Particles and fields·2015
Same author

Measurement of <i>τ</i> polarization in <i>W</i>→<i>τν</i> decays with the ATLAS detector in <i>pp</i> collisions at [Formula: see text].

The European physical journal. C, Particles and fields·2015
Same author

Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections.

Physical review letters·2012

Area of Science:

  • Veterinary Surgery
  • Animal Research Models

Background:

  • Traditional devices for long-term intestinal access in animals often cause infection, tissue reactions, and require single housing.
  • Existing methods can lead to implant damage and complications, compromising animal welfare and research integrity.

Purpose of the Study:

  • To evaluate the efficacy and safety of using intussuscepted nipple valves for establishing long-term intestinal access in dogs.
  • To compare the nipple valve technique with traditional stoma methods regarding post-operative complications and animal quality of life.

Main Methods:

  • Intussuscepted nipple valves were surgically implanted in 14 dogs to create access to the colon, duodenum, or ileum.
  • The study monitored for post-operative complications, leakage, tissue rejection, and assessed the need for single housing or activity restrictions.

Main Results:

  • The nipple valve technique resulted in minimal post-operative complications, no leakage, and no tissue rejection due to the absence of foreign materials.
  • Long-term intestinal access was successfully established in multiple sites in 14 dogs, with some instrumentation exceeding 60 weeks.
  • Instrumented dogs did not require single housing, could participate in outdoor activities, and showed no compromise in quality of life.

Conclusions:

  • Intussuscepted nipple valves offer a superior method for achieving long-term intestinal access in laboratory dogs.
  • This technique enhances animal welfare, simplifies management, and reduces complications associated with traditional intestinal access devices.

Related Experiment Videos