The morphological changes of intestinal mucosa in growing rabbits

The study aimed to increase understanding of digestive function from the development of the digestive tract from suckling to maturity in rabbits. The relative weights of the digestive tract (in relation to body weight) in different segments increase linearly during the rapid growth period between 2 and 8 weeks of age, thereafter intestinal weight gain is slower. An underdeveloped mucosal histology was observed in the hindgut of suckling rabbits at 2 weeks compared with 4 weeks of age. From SEM micrographs, the small intestinal mucosal villi look more slender and finger-like in the suckling period, thereafter becoming broader or tongue-like or plate-shaped in mature rabbits. The micrographs showed a compact arrangement in the underdeveloped hindgut mucosa at 2 weeks, but after weaning as hindgut fermentation becomes significant the mucosa increased in surface area.