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Erythromycin interaction with risperidone or clomipramine in an adolescent
Journal of Child and Adolescent Psychopharmacology
|July 1, 1996
Summary
Adding erythromycin to risperidone and clomipramine regimens can cause adverse behavioral events. This drug interaction, involving cytochrome P450 metabolism, highlights the need for caution with psychotropic medications.
Area of Science:
- Pharmacology
- Neuroscience
- Clinical Toxicology
Background:
- Adverse drug events can occur with psychotropic medications.
- Drug-drug interactions involving cytochrome P450 enzymes are a concern in polypharmacy.