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The acute effects of exercise on bone turnover
L Welsh1, O M Rutherford, I James
1Imperial College School of Medicine at St. Mary's, London, United Kingdom.
International Journal of Sports Medicine
|May 1, 1997
Summary
Moderate exercise appears to increase bone resorption markers within 32 hours, but does not affect bone formation markers. This study investigated short-term bone turnover responses to exercise in healthy men.
Area of Science:
- Exercise physiology
- Bone biology
- Biochemistry
Background:
- Long-term exercise benefits bone mass.
- Short-term effects of exercise on bone turnover remain unclear.
Purpose of the Study:
- Investigate acute effects of exercise on bone remodeling.
- Measure blood and urinary markers of bone turnover post-exercise.
Main Methods:
- Ten healthy young men underwent 30 minutes of treadmill walking.
- Blood and urine samples measured for bone turnover markers (osteocalcin, alkaline phosphatase, pyridinoline, deoxypyridinoline).
- Dual energy X-ray absorptiometry used for bone density and body composition.
Main Results:
- No significant changes in osteocalcin or alkaline phosphatase levels observed.
- Urinary crosslinks (pyridinoline, deoxypyridinoline) significantly increased post-exercise.
- Negative correlations found between crosslinks, osteocalcin, and body fat percentage.
Conclusions:
- Moderate exercise stimulates bone resorption within 32 hours.
- No measurable effect on bone formation detected within 32 hours.
- Longer study duration may be needed to detect bone formation changes.