Related Experiment Video
Updated: Aug 11, 2026

Dopamine Release at Individual Presynaptic Terminals Visualized with FFNs
Published on: August 31, 2009
Neurotransmitter release - four years of SNARE complexes
P I Hanson1, J E Heuser, R Jahn
1Department of Pharmacology, 295 Congress Avenue, Yale University School of Medicine, New Haven, Connecticut 06510, USA. phyllis.hanson@yale.edu
Abstract:
Exocytosis in neurons requires proteins known as SNAREs, membrane proteins that have now been implicated in many intracellular fusion events. SNAREs assemble into stable ternary complexes that are dissociated by the ATPase NSF (N-ethylmaleimide-sensitive factor), working together with SNAPs (soluble NSF attachment proteins). Recent results have shed new light on the mechanisms underlying SNARE (SNAP receptor) complex assembly and disassembly, and suggest changes in models that relate these reactions to vesicle docking and fusion.
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