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Serological diagnosis of HTLV-I/II infections in France
J M Lemaire1, S Voisin, J Coste
1Centre Régional de Transfusion Sanguine, Montpellier, France.
During the last years, important improvements have been made in the field of HTLV-I/II serodiagnosis. The screening tests, which combine higher performances of the sensitivity towards HTLV-I and HTLV-II samples, and better specificity, are manifold. The criteria of positivity by western-blots have been reinforced. As for HIV, some western-blot profiles with no evolution on two successive samples, correspond to non specific HTLV reactions. HTLV-I/II serotyping is easier than before. More effective tools will certainly be available in the coming years for the Blood Transfusion Services and the physicians.
During the last years, important improvements have been made in the field of HTLV-I/II serodiagnosis. The screening tests, which combine higher performances of the sensitivity towards HTLV-I and HTLV-II samples, and better specificity, are manifold. The criteria of positivity by western-blots have been reinforced. As for HIV, some western-blot profiles with no evolution on two successive samples, correspond to non specific HTLV reactions. HTLV-I/II serotyping is easier than before. More effective tools will certainly be available in the coming years for the Blood Transfusion Services and the physicians.