[Immune system cells as mediators in the reaction of other body systems to stress exposure]

This paper first details an acute reaction of mice to the administered syngenic and allogenic live splenocytes from the animals exposed to great emergency. The authors have called it "nonspecific immunogenic shock" as its stages and manifestations which are characteristic of shock are caused only by lymphocytes, but associated with any specific exposure. The most common sequela of nonspecific immunogenic shock may be animal's death within minutes or first days after administration of splenocytes. In this case, marked cataracts (generally after death, but occasionally in life) appear both in recipients and stress-exposed donors. The ability of splenocytes activated by stress in donors to cause sudden or delayed death of most recipients makes the author give the second term of "death transfer" to nonspecific immunogenic shock.