[Immune responsive features in patients with pulmonary tuberculosis complicated by intestinal dysbacteriosis]

Clinical and immunological studies made in 130 patients with various types of pulmonary tuberculosis ascertain that the absolute majority (90%) patients who begin to develop intestinal dysbacteriosis due to long-term chemotherapy have T-cell immunity impairments, which appears as their quantitative shortage and functional insufficiency. There is a marked decrease in T helper levels with subpopulation imbalance and lower Tx/Tc ratios. The applied complex of corrective means produces stimulating and correcting effects on cellular and humoral immunological responses, promotes the increase of T helper counts, by eliminating the imbalance of regulatory subpopulations of T lymphocytes and having a beneficial effect on the clinical and X-ray changes in pulmonary tuberculosis.