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Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
14:52

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Published on: December 11, 2013

Intermittent claudication. A risk profile from The Framingham Heart Study

J M Murabito1, R B D'Agostino, H Silbershatz

  • 1Framingham Heart Study, MA 01701, USA. joanne@fram.nhlbi.nih.gov

Circulation
|July 1, 1997
PubMed

Insights

Intermittent claudication (IC) is a key indicator of increased mortality risk. A new risk profile identifies individuals with IC using factors like age, cholesterol, and smoking, aiding early intervention.

Area of Science:

  • Cardiovascular Medicine
  • Epidemiology

Background:

  • Intermittent claudication (IC) is a significant predictor of mortality and disability.
  • Identifying individuals at risk for IC is crucial for preventative healthcare strategies.

Purpose of the Study:

  • To develop a risk profile for intermittent claudication (IC).
  • To identify individuals at increased risk for IC using established risk factors.

Main Methods:

  • Utilized 38-year follow-up data from the Framingham Heart Study cohort.
  • Developed a risk profile incorporating age, sex, serum cholesterol, hypertension, smoking, diabetes, and coronary heart disease.
  • Employed pooled logistic regression to calculate IC probability based on risk factor levels.

Main Results:

  • A total of 381 men and women experienced intermittent claudication (IC).
  • Key risk factors identified include age, sex, elevated cholesterol, hypertension, smoking, diabetes, and existing coronary heart disease.
  • The developed profile effectively associated these factors with increased IC risk.

Conclusions:

  • The intermittent claudication (IC) risk profile enables physicians to identify high-risk patients during routine visits.
  • The profile facilitates patient education on modifiable risk factors, emphasizing smoking cessation and blood pressure control.
  • Enhanced adherence to risk factor modification strategies holds potential for improving patient survival rates.
Abstract

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