Documented sudden onset of pseudothrombocytopenia
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Updated: Nov 1, 2026

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Published on: May 29, 2021
M E Gschwandtner1, P Siostrzonek, C Bodinger
1Department of Cardiology, Allgemeines Krankenhaus Wien, University of Vienna, Austria.
A 66-year-old male patient was hospitalized for severe heart failure. Within 3 days after admission his platelet count dropped from 148 x 10(9)/l to 3 x 10(9)/l. Pseudothrombocytopenia was diagnosed based on the platelet count of 3 x 10(9)/l in K3-EDTA anticoagulated blood as opposed to 110 x 10(9)/l in sodium citrate. Platelet reactive antibodies were not detectable. To the best of our knowledge, this is the first report of a documented onset of pseudothrombocytopenia.
A 66-year-old male patient was hospitalized for severe heart failure. Within 3 days after admission his platelet count dropped from 148 x 10(9)/l to 3 x 10(9)/l. Pseudothrombocytopenia was diagnosed based on the platelet count of 3 x 10(9)/l in K3-EDTA anticoagulated blood as opposed to 110 x 10(9)/l in sodium citrate. Platelet reactive antibodies were not detectable. To the best of our knowledge, this is the first report of a documented onset of pseudothrombocytopenia.
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