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Updated: Aug 9, 2026
A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Stenting: a new approach to carotid dissection
J DeOcampo1, J Brillman, D I Levy
1Department of Neurology, Allegheny University of the Health Sciences, Allegheny General Hospital, Pittsburgh, PA, USA.
Insights
Fibromuscular dysplasia caused artery blockages leading to stroke. Balloon angioplasty and stenting reopened the carotid artery, restoring blood flow and resolving deficits.
Area of Science:
- Neurology
- Vascular Medicine
- Interventional Cardiology
Background:
- Fibromuscular dysplasia (FMD) is a rare arterial disease.
- Bilateral internal carotid artery (ICA) occlusion can lead to severe cerebrovascular events.
- FMD can affect multiple arteries, including ICAs and vertebral arteries (VAs).
Abstract:
A patient with bilaterally occluded internal carotid arteries had a right hemispheric stroke followed by a left cerebral infarction, secondary to dissection from fibromuscular dysplasia, seen also in the vertebral arteries. The occluded left carotid was reopened and stents placed, with apparent reestablishment of left hemispheric blood flow. The speech and other deficits resolved. Although its use is under investigation, percutaneous balloon angioplasty with stents may be an appropriate intervention when other measures do not prevent progressive ischemic events.
