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Successful birth after intrafallopian transfer of microhatched embryos
D S Castellotti1, E L da Motta, J R Alegretti
1Huntington Centro de Medicina Reprodutiva, São Paulo, Brazil. HUNITNET@BR.HOMESHOPPING.COMBR
Objective:
To present a successful transfer of microhatched embryos to the fallopian tubes via microlaparoscopy.
Design:
Case report.
Setting:
Private practice affiliated with a medical university.
Patient:
A 40-year-old woman with primary infertility, mildly elevated baseline FSH levels, and a history of poor ovarian response to ovulation induction. Her husband had severe oligoospermia after vasectomy reversal.
Intervention(S):
Late luteal leuprolide acetate to pituitary down-regulation followed by pure FSH, 300 IU, and hMG, 300 IU, daily for ovulation induction. Transvaginal oocyte retrieval, intracytoplasmic sperm injection, assisted embryo hatching, microlaparoscopic intrafallopian ET.
Main Outcome Measure(S):
Amniocentesis at the 14th week of gestation revealed a normal karyotype (46,XX), birth of a normal female infant (3700 g).
Result(S):
Establishment of a single, viable intrauterine gestation followed by a vaginal delivery at term.
Conclusion(S):
This case shows the possibility of using assisted-hatched embryos for laparoscopic intrafallopian tube transfer.