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Assisted reproductive technology: the state of the ART
1San Diego Fertility Center, Poway, CA 92064, USA.
Annals of Medicine
|June 1, 1997
Summary
Infertility affects 10% of couples, with causes including tubal disease and ovulatory defects. Assisted reproductive technology (ART) offers effective treatments for conception failure when other methods are unsuccessful.
Area of Science:
- Reproductive Medicine
- Infertility Research
- Assisted Reproductive Technology
Background:
- Infertility impacts at least 10% of reproductive-aged couples globally.
- Common causes include tubal disease, ovulatory dysfunction, endometriosis, and abnormal sperm physiology.
- While some infertility cases are treatable with conventional methods, many require advanced interventions.
Purpose of the Study:
- To provide a comprehensive overview of assisted reproductive technology (ART) techniques.
- To review indications, patient evaluation, and recent advancements in ART.
- To highlight ART as a crucial treatment for intractable infertility.
Main Methods:
- Review of established and emerging assisted reproduction techniques.
- Discussion of in vitro fertilization (IVF) and gamete intrafallopian transfer (GIFT).
- Exploration of related procedures and technological innovations.
Main Results:
- ART encompasses various procedures like IVF and GIFT for conception.
- Patient evaluation and specific indications guide treatment selection.
- Advances include embryo cryopreservation, micromanipulation, and donor gametes.
Conclusions:
- Assisted reproductive technology (ART) is the treatment of choice for selected and long-standing infertility cases.
- Technological advancements are expanding treatment options and success rates.
- A thorough understanding of ART is essential for managing infertility effectively.
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Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic cell—any cell that is not a sex...
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic cell—any cell that is not a sex...
01:27Reproductive Cloning
Reproductive cloning is the process of producing a genetically identical copy—a clone—of an entire organism. While clones can be produced by splitting an early embryo—similar to what happens naturally with identical twins—cloning of adult animals is usually done by a process called somatic cell nuclear transfer (SCNT).
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic cell—any cell that is not a sex...
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic cell—any cell that is not a sex...
01:24In Vitro Fertilization
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
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