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Sphincter-saving resection, or not, for cancer of the midrectum
M Huguier1, C Chastang, S Houry
1Department of Surgery, Hôpital Tenon, Université Paris VI, France.
Background:
The purpose of this study was to compare the time to pelvic recurrence and survival after sphincter-saving resection (SSR) or abdominoperineal resection (APR).
Methods:
Out of the 119 patients with a cancer of the midrectum, 43 had undergone a SSR and 76 an APR for cure. To eliminate bias of a nonrandomized retrospective comparison, an adjustment for baseline prognostic covariates was used.
Results:
Pelvic recurrence rates and survival distribution according to the type of resection did not differ significantly, with P values of 0.31 and 0.95, respectively, by the log-rank test. The Cox regression model incorporated nine binary covariates and the treatment group. Given these nine covariates, treatment did not influence either pelvic recurrence (adjusted P value = 0.62, relative risk = 0.78) or overall survival (adjusted P value = 0.89, relative risk = 1.05).
Conclusion:
These results suggest that, in patients with cancer of the midrectum treated by SSR or APR, recurrence and survival rates are similar.