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Synthesis and antimycobacterial activity of some new 3-heterocyclic substituted chromones
R Gasparová1, M Lácová, H M el-Shaaer
1Department of Organic Chemistry, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia.
Farmaco (Societa Chimica Italiana : 1989)
|April 1, 1997
Abstract:
The aldol synthesis of benzimidazole, benzothiazole and benzothiazolium salt derivatives of chromones is described. The structures of the compounds have been proved by elemental analysis and 1H NMR spectra. The antimycobacterial activity of some of the prepared compounds have been tested in vitro against Mycobacterium tuberculosis (H37Rv) and Mycobacterium fortuitum (1021).