Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Vancomycin-resistant enterococci: clinical, microbiologic, and epidemiologic features

¹Department of Medicine, Northwestern University Medical School, Chicago, IL 60611, USA.

The Journal of Laboratory and Clinical Medicine

|July 1, 1997

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Screening for extended-spectrum beta-lactamase-producing Enterobacteriaceae among high-risk patients and rates of subsequent bacteremia.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2007

Same author

A randomized, open-label, multicenter comparative study of the efficacy and safety of piperacillin-tazobactam and cefepime for the empirical treatment of febrile neutropenic episodes in patients with hematologic malignancies.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2006

Same author

Active surveillance using electronic triggers to detect adverse events in hospitalized patients.

Quality & safety in health care·2006

Same author

Safety, efficacy and pharmacokinetics of linezolid for treatment of resistant Gram-positive infections in cancer patients with neutropenia.

Annals of oncology : official journal of the European Society for Medical Oncology·2003

Same author

Contamination of the clinical microbiology laboratory with vancomycin-resistant enterococci and multidrug- resistant Enterobacteriaceae: implications for hospital and laboratory workers.

Journal of clinical microbiology·2001

Same author

Treatment of 21 cases of invasive mucormycosis with amphotericin B colloidal dispersion.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2001

Vancomycin-resistant enterococci are a growing threat in hospitals, often resistant to multiple antibiotics. High mortality rates underscore the urgent need for effective treatments and prevention strategies.

Area of Science:

Infectious Diseases
Microbiology
Hospital Epidemiology

Background:

Enterococci are significant nosocomial pathogens.
Increasing antimicrobial resistance, particularly vancomycin resistance, is a major concern.
Dissemination of vancomycin-resistant enterococci (VRE) across the US and Europe is documented.

Purpose of the Study:

To highlight the clinical significance of vancomycin-resistant enterococci.
To discuss the challenges in treating VRE infections due to multidrug resistance.
To emphasize the high mortality associated with VRE bacteremia.

Main Methods:

Review of current literature on enterococcal infections.
Analysis of trends in antimicrobial resistance.

Related Experiment Videos

Identification of risk factors for VRE acquisition.

Main Results:

VRE strains exhibit resistance to beta-lactams and aminoglycosides, complicating treatment.
Optimal therapeutic strategies for VRE infections remain undefined.
Attributable mortality for VRE bacteremia is notably high.

Conclusions:

Prevention through infection control and judicious antibiotic use is critical.
Urgent need for development of effective therapies against VRE.
Risk factors such as prolonged hospitalization and prior antibiotic exposure are identified.