Related Experiment Videos
Allogeneic blood stem cell transplantation: considerations for donors
Blood
|August 1, 1997
Summary
Recombinant human granulocyte colony-stimulating factor (rhG-CSF) appears safe for short-term use in peripheral blood stem cell (PBSC) donors. Continued monitoring is recommended, and an international registry is proposed to track long-term safety.
Area of Science:
- Hematology
- Transplantation Immunology
Background:
- Allogeneic transplantation of cytokine-mobilized peripheral blood stem cells (PBSCs) is increasingly common.
- Safety considerations for healthy PBSC donors, particularly regarding recombinant human granulocyte colony-stimulating factor (rhG-CSF), require further clarification.