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Polyclonal staphylococcus endocarditis

E Van Wijngaerden¹, W E Peetermans, S Van Lierde

¹Rega Institute, Catholic University of Leuven, Belgium.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America

|July 1, 1997

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Coagulase-negative staphylococcus (CNS) endocarditis can involve multiple distinct bacterial genotypes. This polyclonality, shown in a case of aortic homograft endocarditis, may impact treatment strategies and antibiotic susceptibility testing for prosthetic device infections.

Area of Science:

Infectious Diseases
Microbiology
Genomics

Background:

Coagulase-negative staphylococcus (CNS) is a leading cause of hospital-acquired infections, including bacteremia and prosthetic valve endocarditis.
While CNS bacteremia can be polyclonal, the clonality of CNS in endocarditis remains largely uncharacterized.
Prosthetic device infections caused by CNS share pathogenic similarities across various devices.