Specificity of micro-leucocyte adherence inhibition test in patients with gastric cancer

Specificity of micro-leucocyte adherence inhibition (LAI) test was studied in patients with gastric cancer. Because of the presence of nonspecific reactions, specificity appeared obscure unless interaction analysis was applied to the results of LAI tests. Application of interaction analysis revealed that only leucocytes from patients with gastric cancer showed specificity to gastric cancer antigen. Further technical improvement is required to eliminate nonspecific reactions which seem to be due to either leucocytes or tumor antigens.