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Absence of a relationship between malnutrition and trachoma in preschool children
1Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21287-9019, USA.
Insights
This study found no association between malnutrition and clinical trachoma in Tanzanian children, despite both conditions being common. Further research into subclinical infections is suggested.
Area of Science:
- Ophthalmology
- Public Health
- Pediatrics
Background:
- Trachoma is a leading cause of preventable blindness globally.
- Malnutrition is prevalent in many developing countries, impacting child health.
- Understanding co-existing conditions like trachoma and malnutrition is crucial for effective public health interventions.
Purpose of the Study:
- To investigate the potential association between malnutrition and clinical trachoma in children.
- To assess the prevalence of trachoma and malnutrition in a trachoma-endemic region of Tanzania.
Main Methods:
- A study involving 189 children aged 1-5 years in Tanzania.
- Clinical examination for active trachoma using the WHO simplified grading scheme.
- Measurement of mid-upper arm circumference to assess nutritional status.
Main Results:
- 57% of children exhibited trachoma, with 9% having severe trachoma.
- Malnutrition, defined by arm circumference or deviation from age-specific means, was common.
- No statistically significant association was found between malnutrition and the presence of trachoma or severe trachoma.
Conclusions:
- While both trachoma and malnutrition are prevalent in the studied population, no direct relationship was identified.
- The findings suggest that malnutrition may not be a significant risk factor for clinical trachoma in this context.
- Further research is recommended to explore the nutritional status of children with subclinical trachoma infections.
Purpose:
To determine if there is an association between malnutrition and clinical trachoma among children in a trachoma endemic region of Tanzania.
Methods:
189 children age one to five were examined by a trained eye nurse for the presence of active trachoma, using the WHO simplified grading scheme. One examiner also measured the arm circumference of the mid-aspect of the upper left arm on the same children. Trachoma was defined as the presence of follicular trachoma (TF) and/or severe trachoma (TI). Malnutrition was defined two ways: a mid-arm circumference of less than 12.5 cm, and a value one standard deviation below the age-specific mean.
Results:
Overall, 57% of children had trachoma, and 9% had severe trachoma. The percentage of children with arm circumference below 12.5 cm varied with age from 96% in the one-year-olds to 35% in the six-year-olds. Using either method of classifying malnutrition, there was no association with trachoma, nor with severe trachoma.
Conclusion:
Trachoma and malnutrition are both common in this sample of children, although no relationship between the two was observed. Further work on the nutritional status in those with subclinical infection may be warranted.
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