[The use of plasmapheresis in treating recurrent aphthous stomatitis]

Plasmapheresis was used in multiple-modality treatment of 33 patients with chronic relapsing aphthous stomatitis. Plasmapheresis was administered on an inpatient basis in an intermittent mode with exfusion of up to 1 liter of plasma per session, 1-3 sessions per course. The efficacy of treatment was assessed from the time course of clinical picture, time of onset of remission and its duration, and metabolic and immunity parameters. Plasmapheresis improved the general status of the patients, accelerated epithelialization of the buccal mucosa, helped attain prolonged remissions, and ameliorated the homeostasis parameters.