[Radiological changes in chronic recurrent multifocal osteomyelitis]

Chronic recurrent multifocal osteomyelitis (CRMO) is a well-established rare clinical and radiographical disease entity, occurring mainly in children and adolescents with a female predominance. It is predominantly located to tubular bones followed by the clavicle and the spine, and other locations are rare. The diagnosis is usually based on a characteristic fluctuating benign course and conventional radiography, if necessary supplemented by microbiological and histopathological examinations to exclude infectious diseases, tumour or tumour-like lesions. It is important to make the diagnosis in order to avoid unnecessary additional diagnostic procedures and give an appropriate therapy. To do this it is necessary to know the radiographic features, which are reviewed here.