[Pharmacotherapy in patients after myocardial revascularization surgery 1991-1995]

The authors discuss in a retrospective study pharmacotherapy administered to 302 patients after revascularization surgery of the heart muscle in 1991-1995 in Konstantinovy Láznĕ. In the introduction they evaluated the ratio of drugs used in secondary prevention of infarctions incl. trends of their use in individual years between 1991-1995 (antiaggregation treatment-beta-blocking agents, calcium channel blockers, ACE inhibitors, hypolipidaemic agent, rapidly acting and retardes forms of nitrates). They evaluate specially medication with beta-blocking agents from the aspect of cardioselectivity, internal sympathomimetic activity, membrane stabilizing effect and period of action. When evaluating pharmacotherapy they found a satisfactory state of affairs as regards administration of antiaggregants and beta-blocking agents. They found reserves as regards the use of ACE inhibitors and hypolipidaemic agents in indicated patients. A relatively high percentage (20%) of patients with angina pectoris persisting after surgery did not take rapidly acting nitrates.