Related Experiment Video
Updated: Aug 8, 2026

Testing for Metacognitive Responding Using an Odor-based Delayed Match-to-Sample Test in Rats
Published on: June 18, 2018
Is it really a mismatch negativity? An assessment of methods for determining response validity in individual subjects
Abstract:
Mismatch negativity (MMN) responses were collected from 86 normal school-age children in response to synthesized speech syllables, /wa/and two variants of /ba/. Waveform characteristics and statistical properties of the responses were analyzed across stimulus conditions in order to assess methods for determining response validity in individuals. Methods were compared using signal detection theory techniques. Criteria based on measurements of response area, onset latency, and duration were the best indicators of response validity. Also a promising indicator of validity was the interval of significance based on Z transformations determined by considering the variance of the underlying noise distribution. Correlations of individual responses with the grand average and integral calculations of the response negativity showed somewhat lower d' values. Statistical methods which utilized response subaverages were the poorest indicators of response validity. Likely the methods are limited primarily by the signal to noise ratio of the MMN compared to the underlying physiologic noise. Improvement of the signal to noise ratio remains a significant factor in the interpretation of MMN for individual subjects.
More Related Videos
08:05Measuring Statistical Learning Across Modalities and Domains in School-Aged Children Via an Online Platform and Neuroimaging Techniques
Published on: June 30, 2020
04:04Transauricular Vagus Nerve Stimulation and Electroencephalographic Assessment in Disorders of Consciousness
Published on: July 11, 2025
Related Concept Videos
Reliability and Validity
Introduction to the Sign Test
Sign Test for Matched Pairs
To conduct the sign test, we first calculate the differences in value between...
Comparing Experimental Results: Student's t-Test
Friedman Two-way Analysis of Variance by Ranks
McNemar's Test