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N-[2-(1-azabicyclo[3.3.0]octan-5-yl)ethyl]-2-nitroaniline, a potent muscarinic agonist
1Drug Discovery Research Department, Sanwa Kagaku Kenkyusho Co., Ltd, Mie, Japan.
Chemical & Pharmaceutical Bulletin
|July 1, 1997
Abstract:
The muscarine receptor agonist SK-946, an aniline derivative with a characteristic bicyclo amine, was found. We describe a new synthetic method for 1-azabicyclo[3.3.0]octane and describe the biological activity of SK-946.