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The Escherichia coli cell cycle, cell division and ppGpp: regulation and mechanisms
1Institut Jacques Monod, CNRS, Université Paris 7, Paris, France.
Folia Microbiologica
|January 1, 1997
Abstract:
The literature demonstrating tight regulation of the Escherichia coli cell cycle is reviewed. Recent evidence is presented indicating that the normal rod cell shape can be abandoned, allowing growth as a coccus, either by increasing the amount of the division proteins FtsZ, FtsA and FtsQ, or by increasing the pool of the nucleotide ppGpp. It is argued that ppGpp may be a cell cycle signal in E. coli.