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[Relationship between mitral valve prolapse and arrhythmogenic right ventricular disease]
A M Costa1, I G Maia, F Cruz Filho
1Hospital Pró-Cardíaco/Pró-Ritmo-Rio de Janeiro.
Arquivos Brasileiros De Cardiologia
|December 1, 1996
Summary
Patients with mitral valve prolapse often have ventricular arrhythmias originating from the right ventricle. This study found a strong association between mitral valve prolapse, arrhythmogenic right ventricular disease, and prolonged Qtc intervals.
Area of Science:
- Cardiology
- Electrophysiology
- Cardiac Imaging
Background:
- Mitral valve prolapse (MVP) is a common valvular condition.
- Ventricular arrhythmias can occur in patients with MVP.
- The origin and mechanisms of these arrhythmias require further investigation.
Purpose of the Study:
- To evaluate features of ventricular arrhythmias in patients with mitral valve prolapse (MVP).
- To determine the origin of ventricular ectopic beats in MVP patients.
- To investigate the association between MVP, arrhythmias, and ECG parameters.
Main Methods:
- Studied 25 patients with MVP and ventricular arrhythmias.
- Utilized 24-hour Holter monitoring and high-resolution ECG (HRECG).
- Analyzed QTc intervals and ectopic beat morphology to determine ventricular origin.
Main Results:
- High incidence of ventricular arrhythmias (>720 beats/24h) in 92% of patients.
- Ventricular arrhythmias originated from the right ventricle in 85% of cases.
- Prolonged QTc intervals were observed in 52% of patients.
Conclusions:
- High incidence of ventricular arrhythmias in MVP patients, often originating from the right ventricle.
- Strong association noted between MVP, arrhythmogenic right ventricular disease, and QTc prolongation.
- Findings suggest a potential global myocardial disease in some MVP patients with arrhythmias.