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Published on: April 12, 2022
Conservative management of osteoradionecrosis
1Ontario Cancer Institute/Princess Margaret Hospital, Department of Dentistry, Toronto, Canada.
Abstract:
A retrospective records analysis of 32 patients with mandibular osteoradionecrosis seen between August 1960 and September 1995 was undertaken to determine the effectiveness of nonsurgical/nonhyperbaric oxygen conservative management. Two patients died before final analysis. Of those alive, 65.5% of patients were spared resection, having lesions resolve (48.3%), improve (3.4%), or asymptomatically stabilize (13.8%). Sequestrum production allowing "gentle" removal predicted a more favorable clinical course when managed conservatively compared with nonsequestrating lesions (p < 0.05). Criteria to define clinical osteoradionecrosis are proposed.
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