Preoperative assessment of the implantable middle ear pump system using CT scans and conventional X-rays of the...

A completely implantable micropump system for drug delivery has recently been developed. After implantation in the temporal bone, this microdosage system enables application of drugs into the middle ear and round window area. Successful application of this new technology depends upon a suitable fit of the micropump within the patient's temporal bone. To obtain information about the fit before surgery, we analyzed 50 cadaver temporal bone specimens before total mastoidectomy, using conventional X-ray and spiral CT scans for water volume determination. Spiral CT is a feasible method for preoperative planning of the surgical implantation of the implantable middle ear micropump system (TI-DDS). The best parameter for a preoperative judgment is the volume of the mastoid cavity, as determined by CT. Implantation may be recommended when the mastoid volume, as measured by CT, is greater than 6.6 ml. To be certain that the implantable drug delivery system will be implantable, a cut-off value of 9.3 ml seems to be advisable. Spiral CT imaging is of great value as a tool for testing implantation preoperatively. The imaging is accomplished in approximately 30 seconds. Our preliminary results with cadaveric temporal bones are encouraging. Further studies are needed in order to transfer the results to a clinical implantation situation.