Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intensive insulin therapy in clinical practice

P D Home1

  • 1Newcastle Diabetes Services, University of Newcastle upon Tyne, UK.

Diabetologia
|July 1, 1997
PubMed
Summary

Achieving optimal blood glucose control with current tools is challenging. Effective insulin therapy requires patient and professional expertise, alongside self-motivation for lifestyle adjustments.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessment of hypoglycaemia during basal insulin therapy: Temporal distribution and risk of events using a predefined or an expanded definition of nocturnal events.

Diabetes & metabolism·2017
Same author

Glycaemic control and hypoglycaemia with insulin glargine 300U/mL versus insulin glargine 100U/mL in insulin-naïve people with type 2 diabetes: 12-month results from the EDITION 3 trial.

Diabetes & metabolism·2017
Same author

Clinical use of the co-formulation of insulin degludec and insulin aspart.

International journal of clinical practice·2016
Same author

Relationship of glycaemic control and hypoglycaemic episodes to 4-year cardiovascular outcomes in people with type 2 diabetes starting insulin.

Diabetes, obesity & metabolism·2015
Same author

Plasma insulin profiles after subcutaneous injection: how close can we get to physiology in people with diabetes?

Diabetes, obesity & metabolism·2015
Same author

Biosimilar insulins: guidance for data interpretation by clinicians and users.

Diabetes, obesity & metabolism·2015

Area of Science:

  • Endocrinology
  • Metabolic Disorders
  • Diabetes Management

Background:

  • Optimal blood glucose control remains a significant challenge for individuals with diabetes, often complicated by hypoglycemia and lifestyle restrictions.
  • Current insulin preparations and monitoring tools present limitations in achieving ideal glycemic targets.
  • Evidence suggests that achieved glycemic control is largely independent of insulin delivery frequency (≥2 injections/day) due to physiological and behavioral factors.

Purpose of the Study:

  • To highlight the complexities in achieving optimal blood glucose control with existing diabetes management tools.
  • To emphasize the critical role of patient and healthcare professional expertise in insulin therapy.
  • To underscore the necessity of patient self-motivation for successful lifestyle modifications in diabetes management.

Main Methods:

  • Review of existing evidence on insulin absorption profiles and their reproducibility.
  • Analysis of factors influencing glycemic control, including insulin delivery methods and human behavior.
  • Discussion of the expertise and self-motivation required for effective diabetes management.

Main Results:

  • Current insulin delivery methods and monitoring tools often lead to suboptimal blood glucose control.
  • Insulin absorption profiles are unphysiological and poorly reproducible, contributing to control difficulties.
  • Effective glycemic control relies heavily on the informed expertise of both patients and healthcare providers, coupled with strong self-motivation.

Conclusions:

  • Achieving optimal blood glucose control necessitates a high level of expertise and informed decision-making from both patients and professionals.
  • Patient self-motivation is crucial for implementing necessary lifestyle changes to complement insulin therapy.
  • Future advancements in insulin delivery aim for automatic control to overcome current limitations.

Related Experiment Videos